Found 277 matching trials
Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors PHASE2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cell...
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Duke Comprehensive Cancer Center
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Effect of Cladribine Treatment on Microglial Activation in the CNS N/A To evaluate the effect of cladribine treatment on microglial activation wit...
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Active Not Recruiting
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HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors PHASE1 This study is a clinical trial to determine the safety of inoculating G207 ...
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University of Alabama at Birmingham Cancer Center
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Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System PHASE1 This pilot clinical trial studies the side effects and the best way to give...
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Children's Hospital Los Angeles
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Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System PHASE2 RATIONALE: Drugs used in chemotherapy, such as temozolomide, use different ...
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Mayo Clinic Scottsdale
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Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors EARLY_PHASE1 This early phase I trial studies the feasibility of giving memantine for th...
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Mayo Clinic in Rochester
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A Prospective, Open-label, Randomized Controlled, Multicenter Clinical Study of MSD-HSCT Using a TBI or TMLI Conditioning Regimen for Pediatric ALL PHASE2 This study aims to compare the effects of two different conditioning regime...
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The First Affiliated Hospital of Zhengzhou University
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Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL PHASE2 RATIONALE: Drugs used in chemotherapy work in different ways to stop the gr...
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Krankenanstalten Gilead gCmbH Neurochirurgische Klinik
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Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL PHASE2 Ph-like ALL is a recently recognized high-risk subgroup and the optimal the...
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Department of Hematology, Nanfang Hospital
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Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL PHASE2 Based on the pediatric-inspired, PEG-L-asparaginase-intensified and MRD-dir...
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Department of Hematology, Nanfang Hospital
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